Guanidium isothiocyanate is a chemical supplied by Genei. Chemically, Guanidium isothiocyanate is a salt of guanidine. It is a very strong chaotropic agent. It is a protein denaturant and is commonly used in molecular biology to understand and study protein folding. Guanidium isothiocyanate is used in research labs during nucleic acid extraction using the guanidium thiocyanate-phenol chloroform extraction. Here, guanidium isothiocyanate is used for its chaotropic nature to bind proteins and purify nucleic acids. This yields genomic DNA of better purity and prevents protein contamination. In RNA extraction protocols, it is used for prevention of the action of RNA and DNA degrading enzymes and to separate nucleic acids from proteins. It is also useful in cell lysis buffers to disrupt the cell membranes. Guanidium isothiocyanate has the following features:

Chemical formula: C2H6N4S

Molecular weight: 118.16 g/mol

Product specifications:

Product name: Guanidium isothiocyanate

Brand: Genei

PI number: FC36

Catalogue number: 613600600501730

Quantity: 50 g

Storage: Store at room temperatre

Purity: > 99%