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RICK Blocking Peptide-301785

RICK Blocking Peptide-301785

₹ 14,124.00 *
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  • Brand: Cayman Chemical
  • Catalog No.: 301785
  • Quantity/Unit: 200 µg/Pack
  • Shipping timeline will be mentioned in quote

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Min Orderable Qty : 1 Pack


For lab/research use only, unless otherwise specified

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To be used in conjunction with Caymans RICK polyclonal antibody (Catalog No. 160785) to block protein-antibody complex formation during immunochemical analysis of RICK Apoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase that regulates apoptosis was recently identified and designated RICK for RIP-like interacting CLARP kinase.1 RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. The RICK kinase domain has high sequence homology to that of RIP. Overexpression of RICK promotes the activation of caspase-8 and Fas-induced apoptosis. RICK represents a novel kinase that regulates Fas-induced apoptosis. The mRNA for RICK is expressed in multiple human tissues.1