Tris hydrochloride by MP Biomedicals is a high grade reagent. Also known as, tris(hydroxymethyl)aminomethane, This is an organic compound which is broadly used as a component of buffer solutions. It contains a primary amine and thus undergoes the reactions associated with typical amines, such as condensations with aldehydes. This reagent is available as a white crystalline powder which is soluble in water. It has a melting point at around 175 - 176 C and a boiling point of 219 C. CAS Number: 1185-53-1 Quantity provided: 1 kg per bottle Chemical formula: NH2C(CH2OH)3 HCl Molecular weight: 157.60 Tris hydrochloride has a wide range of applications in biological and chemical industries. It is used in various molecular biology experiments as a component of buffers like TAE and TBE buffers, especially for solutions of nucleic acids. Its buffer range coincides with the physiological pH typical of most living organisms which is favourable. Since Tris inhibits a number of enzymes, it should be used with care when studying proteins. It is also used as a primary standard to standardize acid solutions for chemical analysis, and to increase the permeability of cell membranes. In the treatment of metabolic acidosis, Tris is used as an alternative to sodium bicarbonate.