PAROXETINE HYDROCHLORIDE HEMIHYDRATE is supplied by Merck (Sigma-Aldrich). It appears as a white powder and has a purity of 98% (HPLC). It is utilized as:

as an antidepressant to study its effects on neural stem cells (NSCs) from embryonic rat hippocampus in vitro

as a CYP 2D6 inhibitor to study its effects on the in vitro production by human recombinant CYP 2D6 of the phenolic metabolites

as an antidepressant to study its effects on the expression of pituitary adenylate cyclase activating polypeptide (PACAP), its receptors and brain-derived neurotrophic factor (BDNF) in rat primary hippocampal neurons

PRODUCT SPECIFICATIONS:

Name: PAROXETINE HYDROCHLORIDE HEMIHYDRATE

Brand: Merck (Sigma-Aldrich)

Pack size: 50MG

Catalog number: P9623-50MG

PRODUCT FEATURES:

Synonym: (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride hemihydrate, Paroxetine HCl

CAS Number: 110429-35-1

Empirical Formula: C19H20FNO3 HCl .5 H2O

Molecular Weight: 374.83