Proteinase K (for 10mg) is a highly active serine protease with broad cleavage specificity on native and denatured proteins. Proteinase K is widely used in the purification of native RNA and DNA from tissues or cell lines, as well as for many other applications. Active in a wide range of temperatures and buffers with optimal activity between 20C and 60C and a pH between 7.5 and 12.0. Store lyophilized powders at 20 C. Store solutions at 4 C