Metabolite of cholesterol produced in the brain by the action of CYP46A1 thereby regulating brain cholesterol homeostasis. Cerebrospinal fluid content of 24(S)-hydroxycholesterol is reduced in Alzheimers disease patientsEndogenous agonist for the nuclear receptor LXR2. Cerebrospinal fluid content of 24(S)-hydroxycholesterol is reduced in Alzheimers disease patients. Induces RIPK1-dependent necrosis-like cell death in the absence of caspase-84.; Purity: > 98%; Molecular Weight: 402.66; Form/Appearance: powder, 5 mg