CBX2 is a component of the polycomb repressive complex 1 and represses protein expression.1 The chromodomain regions of CBX2 recognizes histone H3 trimethyl lysine 9 (H3K9me3) or trimethyl lysine 27 (H3K27me3).2,3,4 CBX2 knock-out mice have impaired spleen formation, T cell expansion, and inactivation of the X chromosome, which can be lethal in some cases.5 This protein product contains the chromodomain region of CBX2. Technical Information Synonyms CDCA6 Cell Division Cycle Associated 6 Chromobox Protein Homolog 2 (Drosophila Pc Class) M33 MGC10561 Modifier 3 SRXY5 Purity 90% Source recombinant N-terminal GST-tagged protein expressed in E. coli MW 38.2 kDa Formulation 50 mM TRIS, pH 8.0, containing 150 mM sodium chloride and 20% glycerol