NITISINONE is supplied by Merck (Sigma-Aldrich). It is utilized:

to induce liver injury

to treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenase

in supplemented water to block the accumulation of toxic metabolites in human hepatocyte engrafted mice

to study its effect on bacterial pyomelanin productio.

PRODUCT SPECIFICATIONS:

Name: NITISINONE

Brand: Merck (Sigma-Aldrich)

Pack size: 10MG

Catalog number: SML0269-10MG

PRODUCT FEATURES:

Synonym: 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-3-(2-naphthyl)-D-alanyl-L-leucyl-L-arginyl-L-prolylglycinamide acetate salt hydrate

CAS Number: 86220-42-0

Molecular Weight: 1322.47

Synonym: 2-(2-Nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione, 2-[2-Nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione, NTBC, Nitisone, SC 0735

CAS Number: 104206-65-7

Empirical Formula: C14H10F3NO5

Molecular Weight: 329.23

Assay: 95% (HPLC)

Form: powder

Color: white to brown

Solubility: DMSO: 5 mg/mL